BIOL121 Lecture Notes - Lecture 6: Mediastinum, Lingual Tonsils, Thymosin

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Immune cells lymphocytes: lymph is a fluid tissue similar to plasma, lymphatic vessels, lymphoid tissues and organs. Where lymphocytes are formed and where they mature. Red bone marrow and the thymus: secondary lymphoid tissues. T lymphocytes (thymus dependent: cytotoxic t cell, helper t cell, memory t cell, suppressor t cell. B lymphocytes (bone marrow derived: plasma cells, memory b cells. Lymph: fluid connective tissue, similar to plasma but less proteins, contains lymphocytes, macrophages and pathogens (foreign cells, foreign proteins and cancer cells) Lymphatic tissues valves similar to those in veins: lymphatic vessels are low in pressure, lymphatic vessels rely on respiratory and skeletal muscle pumps to move fluid, connective tissue dominated by lymphocytes, non-distinct borders. Tonsils (left and right palatine and lingual tonsils. Mucose-associted lymphoid tissues (malt: appendix, digestive epithelium. Thymus: located in mediastinum, largest just before puberty (~40g), atrophies in advanced years (~12g by 50 years old, produces thymosin hormones to promote maturation of t lymphocytes, secondary lymphoid organs.

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