CEDB20003 Lecture Notes - Lecture 4: Electrochemical Gradient, Membrane Transport Protein, Sodium-Potassium Alloy
13 Aug 2018
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Document Summary
Proteins associated with lipid bilayers in various ways. Detergent will dissolve the membrane allowing you to access the protein. Tm proteins are amphillic side chains of amino acids in tm domain are mostly non-polar (yellow, green) polar peptide bonds of aa chain: aa hydrogen bond with each other. Anything that is charged is going to be polar. Mediate attachment to environent permeability of pure phospholipid bilayers to various classes of solutes. Protein free lipid bilayers are impermeable to certain solutes. Why a lipid bilayer is impermeable to ions and large polar molecules. Transport proteins provide a pathway for solute movement across lipid bilayers transport proteins active vs. passive transport transporter mediated active transport. P-type atpase pumps channel proteins and gating the membrane potential has to let things across and out for the cell to live. Will mostly go from high conc to low conc. Concentration gradient drive passive transport of uncharged solutes.
