CEDB20003 Lecture Notes - Lecture 18: Mdm2, Cytochrome C, Dorsal Root Ganglion

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Cells must proliferate and differentiate and some must also die. The relative rates of these events control the rate of production of tissues. Many tissues have constant rates of cell proliferation and cell death. Rates of these things controls the rate of production of these tissue. Division and death depends upon intracellular mechanisms that are. There are new cells continuously being generated regulated by extracellular signals. Systemic controls such as growth hormone secreted by the pituitary which acts on the liver and other organs to secrete insulin like growth factor 1, which in turn promotes cell survival and proliferation. Tissue remodeling where they change structure when cell death is at a higher level. Bacteria enter the organ and the villi go through cell death and remodels to form a little house for the bacteria. Regulated cell death (apoptosis) is a normal part of tissue development. There are individual organisms that respond to specific signals.

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