BIO1011 Lecture Notes - Lecture 4: Citric Acid Cycle, Pyruvic Acid, Glycolysis

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Bio1011 lecture 4 - energy transformation in cells, cellular. But fast oxidation isn"t very useful for life. The breakdown of food by heterotrophic metabolism takes place in a number of stages known collectively as catabolism. Takes place in the cytosol of the eukaryote cell. Atp is expended during conversion of: glucose to glucose-6-p fructose-6-p to fructose-1,6-p2. By the end of the priming sequence, one glucose molecule has been converted to two molecules of glyceraldehyde-3-p. The following reactions (energy pay-off stage) sees energy being produced from the breakdown of the sugar. This is an example of substrate-level phosphorylation: the energy of the exothermic reaction is sufficient to directly transfer the phosphate from the substrate to adp, a second substrate level phosphorylation completes glycolysis. Net result of glycolysis: 1 glucose -> 2 pyruvate. 2 atp in 4 atp and2 nadh out. Glycolytic breakdown of glucose to pyruvate results in a net energy output of 2 atpand2.

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