PHY3171 Lecture Notes - Lecture 2: Carotid Sinus, Preganglionic Nerve Fibers, Pulmonary Stretch Receptors

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Sympathetic = blood vessels (arteries, arterioles, venules and veins) + the heart (both cardiac. 6/03/18 pacemaker + ventricular mussel parts: hr + contractility. Parasympathetic = mainly the heart (cardiac pacemaker parts: only hr. Chemoreceptors in carotid sinus changes in oxygen in blood detect hypoxia. Chemo in brain change in ph via carbon dioxide in blood. Preganglionic (sympathetic) is outside the tissue: ach acts on nicotinic receptors, stimulates release of noradrenaline from post. Preganglionic arise from brain stem: are very long go all the way to target tissue, ach acts on nicotinic receptors, stimulates release of ach from post. Vasoconstrictor centre = rostral ventrolateral medulla: main source of all pre motor sympathetic drive to blood vessels, without bp will be low. Nucleus tractus solatarius ventricular muscle: where all sensory nerves first converge into the brain. Main sympathetic nerve pathway to heart + blood vessels.

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