HUBS1403 Lecture Notes - Lecture 8: Spindle Apparatus, Endoplasmic Reticulum, Centrosome

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Lecture'8'–'Intracellular'Compartments'
!
1. Label!a!cell!and!discuss!the!function!of!each!organelle.!
Organelle!
Function!
Cytoskeleton!
Serves!as!scaffold!that!helps!to!determine!shape!and!contents!
Aids!movement!of!organelles!within!the!cell!
Centrosome!
Pericentriolar!material!of!centrosome!contains!tubulins!that!build!microtubules!
Pericentriolar!material!forms!mitotic!spindle!
Cilia!and!flagella!
Cilia!moves!fluid!along!cell’s!surface!
Flagellum!moves!entire!cell!
Ribosomes!
Protein!synthesis!
Endoplasmic!
reticulum!
Rough!ER!synthesises!glycoproteins!and!phospholipids!that!are!transferred!into!
organelles!
Smooth!ER!synthesises!fatty!acids!and!steroids!
Golgi!complex!
Modifies,!sorts,!packages!and!transports!proteins!
Forms!secretory!vesicles!that!discharge!processed!proteins!
Lysosomes!
Digest!substances!that!enter!cell!via!endocytosis!
Carry!out!digestion!of!worn!out!organelles!(autophagy)!
Implement!digestion!of!entire!cell!(autolysis)!
Mitochondria!
Generate!ATP!from!aerobic!respiration!
Nucleus!
Controls!cellular!structure!
Directs!cellular!activities!
Produces!ribosomes!in!nucleoli!
Peroxisomes!
Oxidises!amino!acids!and!fatty!acids!
Detoxifies!harmful!substances!
Proteasome!
Degrades!unneeded,!damaged,!or!faulty!proteins!
!
2. What!is!a!chromosome?!
A!thread!like!structure!of!nucleic!
acids!and!protein!found!in!the!
nucleus,!carrying!genetic!
information!in!the!form!of!genes.!
3. What!is!a!gene?!
A!unit!of!hereditary,!which!is!
transformed!from!a!parent!to!
offspring!and!is!held!to!
determine!some!characteristic!
of!the!offspring.!
!
! !
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Document Summary

Function: serves as scaffold that helps to determine shape and contents, aids movement of organelles within the cell, pericentriolar material of centrosome contains tubulins that build microtubules, pericentriolar material forms mitotic spindle, cilia moves fluid along cell"s surface, flagellum moves entire cell, protein synthesis, rough er synthesises glycoproteins and phospholipids that are transferred into. Implement digestion of entire cell (autolysis: smooth er synthesises fatty acids and steroids, modifies, sorts, packages and transports proteins, forms secretory vesicles that discharge processed proteins, digest substances that enter cell via endocytosis, carry out digestion of worn out organelles (autophagy, generate atp from aerobic respiration, controls cellular structure, directs cellular activities, produces ribosomes in nucleoli, oxidises amino acids and fatty acids, detoxifies harmful substances, degrades unneeded, damaged, or faulty proteins.

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