BIOL1008 Lecture Notes - Lecture 14: Reference Genome, Genomics, Chromosome
Document Summary
Imagine you are a geneticist who runs a clinic for teegos. Teegos are small, green, friendly, blob-like creatures that eat metal and live to approximately 50 years old. An unwell adult teego comes into your genomics centre. You believe that genome sequencing may give you the information you need to help your patient. Unlike humans, teegos have very small genomes: 70 base pairs contained on a single chromosome. Teegos are monoploid, which means they have only one copy of their chromosome in each cell. Thanks to the teego genome project , you have access to a reference genome for the teego species- the sequence of all 70 dna bases of a randomly chosen healthy. By comparing your patient"s genome to this reference, you may be able to find differences that explain the symptoms you can see. The first step is to send your patient"s dna to the lab for whole genome sequencing.
