PHAR2822 Lecture Notes - Lecture 1: Probiotic, Diphenoxylate, Rotavirus

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28 Aug 2018
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Diarrhoea is the increased frequency of liquid or semi-liquid stools, results in loss of fluids and salts which leads to dehydration. When body levels of water and electrolytes become sub-optimal for normal functionaling and well-being, dehydration exists. To function and remain healthy the body requires the correct internal balance of water and electrolytes. Inflamed intestinal lining impairs water absorption from waste or lining may also leak water. May show symptoms of abdominal cramps, nausea/vomiting also. Bacteria (campylobacter, c. difficile, e. coli, salmonella) Inflammatory bowel disease chrohn"s disease, ulcerative colitis. Replace fluids to restore body fluid levels. Fluid and electrolyte therapy oral rehydration solutions (ors) Frozen preparations had a lower refusal rate and higher success rate. At least 5ml per kg per hour. Bottle feeding continue formula and give ors. Solids recommence solids within 24 hours with easily digested foods. Opioid antidiarrhoeals short term use for control of symptoms during periods of social inconvenience (not to be used in kids)

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