PHAR2822 Lecture Notes - Lecture 2: Titration, Baclofen, Pethidine
Document Summary
~ 25% believe it has no side effects ~ 25% believe it causes drowsiness. ~ (cid:858)(cid:861)% don"t know whether or not it can be harmful. Of those who believe that it can be harmful, 55% overestimate the number of tabs/caps required. ~ (cid:861)(cid:856)% don"t know or believe it can"t be fatal. Of those who believe that it can be fatal, 65% overestimate the number of tabs/caps required. 35% estimate 100 or more tabs/caps required. Paed: not in pharmacy (specialist only) Adult: 75 150mg d in 2 or 3 doses (cid:523) (cid:858)(cid:856)(cid:856)mg d(cid:524) (cid:498)diclofenac (cid:857)(cid:861)(cid:856) mg/day is the most effective nsa)d available at present(cid:499) (cid:523)costa (cid:858)(cid:856)(cid:857)(cid:862), Theoretically reduced gi adrs reduced cox-i inhibition adrs still present. Indications: pain associated with inflammation, pyrexia good in combination with regular paracetamol. Precautions: cv risk, angina, vascular surgery, asthma, coagulopathies, dehydration, gi (esp bleeding), renal, Adrs: nvd, gi bleed, liver enzymes, ht, electrolyte, renal. Breastfeeding: non-selective, appear safe, selective: less data, appear safe.
