PCOL2605 Lecture Notes - Lecture 11: Antileukotriene, Muscarinic Acetylcholine Receptor M3, Beta Blocker
23 Oct 2018
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Document Summary
Explain the basic pathophysiology and triggers of asthma. Discuss the mechanism of action, and adverse effects of drugs used in the treatment of asthma including: Short acting 2 receptor agonists - long acting 2 receptor agonists - corticosteroids. Explain the benefits of an asthma action (management) plan. Understand the basic pathology of chronic obstructive pulmonary disease. Discuss the treatment options for chronic obstructive pulmonary disease. Involves eosinophils, macrophages, neutrophils, t lymphocytes, mast cells and ige. Inflammation results in contraction of the smooth muscle airways, swelling of the airway wall and mucous secretion. Patients experience; wheezing, shortness of breath, chest tightness, cough, dyspnoea. 10-12% of adults and 10-15% of children in. Allergens including pollens, moulds, cats, house dust mites, shellfish, nuts. Over 80% of patients who suffer from asthma also suffer from allergic rhinitis. Up to 40% of patients who suffer from allergic rhinitis also suffer from asthma. The parasympathetic nervous system innervates bronchiole smooth muscle.
