101684 Lecture Notes - Lecture 11: Obsessive–Compulsive Disorder, Generalized Anxiety Disorder, Tricyclic Antidepressant
3 Sep 2018
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Hans selye: called the consistent physiological reaction to stress the general adaption syndrome, short term alarm phase (sns, resistance phase (longer term, involves hormone response, exhaustion phase (depletion, can lead to illness and depression) Obsessive compulsive disorder: ocd an exaggeration of normal human tendencies (perhaps cause by absence of some form of. It could be caused by genetic predisposition, brain damage at birth, encephalitis and head injuries. Increased activity in the orbitofrontal cortex, cingulate cortex and caudate nucleus (a part of basal nuclei) observed in ocd patients. Simplistic, but makes sense: gaba is in inhibitory neurotransmitter, gaba arrival at the synapse permits cl- entry into neurons, benzodiazepine acts on gaba receptors and facilitates the influx of cl- (this is called "alloseric modulation" "a ligand which binds to a receptor at a site distinct from that of the endogenous agonist: benzodiazepine has an anxiolytic (anxiety reducing) effect.
