101684 Lecture Notes - Lecture 14: Dementia With Lewy Bodies, Alois Alzheimer, Toxic Heavy Metal
3 Sep 2018
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Document Summary
What does degenerative mean: degenerative means there is gradual atrophy of brain tissue, leading to various symptoms that include, memory loss, dementia. Progressive dementias: cortical dementias, alzheimer"s disease, pick"s disease. Subcortical dementias: huntingdon"s disease, parkinson"s disease, aids dementia, creutzfeldt-jakob disease, mixed dementias, lewy body dementia, multi-infarct dementia (mid) Potentially static dementias: toxic conditions, alcohilic dementia, heavy metal poisoning. Initial focus on progressive cortical dementia (alzheimer"s disease: then 2 progressive subcortical dementias, parkinsons and huntingdons diseases. Alzheimer"s disease (ad: named after physician alois alzheimer, who described a form of pre-senile dementia in the early 1900"s. Incidence increases exponentially from age 65-85: the major impairment is memory loss, ad develops in 3 stages, 0-3 yrs. Spactial perception declines: memory for recent years is impaired, disorientation in time and pkace, concentration impaired. Impaired verbal fluency: 2-3 years, memory failure progresses, difficulty understanding speech. Judgement and the capacity for abstract thought disappears: 8-12 years.
