300889 Lecture Notes - Lecture 6: Active Transport, Iatrogenesis, Neoplasm

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14 Nov 2018
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Inflammatory physiological response of living tissue to injury. Usually named from organ affected and has suffix -itis" (e. g. tonsillitis: growth disorders disease characterised by abnormal growth include adaptations to changing circumstances. The heart enlarges (by hypertrophy) in patients with high blood pressure. Neoplasia is the most serious group of diseases characterised by growth disorders. Suffix -oma" usually signifies that the abnormality is a solid tumour. Injury and disorder repair mechanical injury or trauma leads directly to disease, the precise characteristics of which depend upon the nature and extent of the injury. Progress of disease depends on body"s reaction to it. Repair mechanisms may be defective due to senility, malnutrition, excessive mobility, presence of foreign bodies and infection: metabolic and degenerative disorder metabolic and degenerative disorders are numerous and heterogeneous. Some metabolic disorders are congenital (inborn errors of metabolism) and are inherited via defective parental genes. Other metabolic disorders are acquired (diabetes) but there may be a genetic predisposition.

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