400621 Lecture Notes - Lecture 12: Bacteroides Melaninogenicus, Prevotella Intermedia, Prevotella

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Prevotella spp. are members of the oral, vaginal, and gut microbiota and are often recovered from anaerobic infections of the respiratory tract. These infections include aspiration pneumonia, lung abscess, pulmonary empyema, and chronic otitis media and sinusitis. They have been isolated from abscesses and burns in the vicinity of the mouth, bites, paronychia, urinary tract infrection, brain abscesses, osteomyelitis, and bacteremia associated with upper respiratory tract infections. Prevotella spp. predominate in periodontal disease and periodontal abscesses. Research of human microbiota show that human gut mainly inhabited by two phyla of bacteria: Firmicutes and bacteroidetes, the latter mostly dominated by. Prevotella and bacteroides are thought to have had a common ancestor. Formally, the two genera were differentiated in 1990. However classification is still undergoing, for example bacteroides melaninogenicus has been reclassified and split into prevotella melaninogenica and. Either prevotella or bacteroides dominates the gut and they were proposed to be antagonistic. Prevotella is more common in non-westernised populations consuming plant-rich diet.

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