IMED2003 Lecture Notes - Lecture 3: Systematic Review, Meta-Analysis, Summary Statistics

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What can systematic reviews synthesise: quantitative studies, meta-analysis, or narrative synthesis. Advantages of systematic reviews: qualitative studies, aggregate or integrate findings from primary qualitative research studies into themes or metaphors, quantitative and qualitative studies, mixed-methods review. Steps in quantitative systematic reviews: formulate the question, question should be clearly focused and defined using the pico method, question should make sense clinically. Ideally, not recently reviewed: decisions to be made about the methods for: Synthesis before commencing review: define the eligibility criteria for the systematic review, use of explicit, predefined criteria: For including and excluding studies (eligibility criteria)- important feature of systematic reviews: eligibility critera for systematic reviews of the effects of interventions. If often hardest part of the review process. Contacting industry and other relevant entities for unpublished or ongoing trial data: avoid publication bias. Locate studies that have not already been published and ongoing or planned studies in the area.

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