IMED2004 Lecture Notes - Lecture 4: Rubella Virus, Cell Migration, Fetus
25 Mar 2020
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Document Summary
Lecture 4 & 5 : embryology i & ii. Fetal period: formation of the embryo is directed by genes but the sequence of genes is influenced by environmental input, cell division, mitosis, apoptosis, programmed cell death. Signals from adjacent tissues that induce change: cavity formation, pumping of fluid, across membranes to form a cavity, cell migration, pseudopodia, allow migration to different areas, folding to rearrange flat layers into tubes within tubes. Is also comes out with a layer of follicular cells (cumulus cells) from the ovary . If more- then there will be one more with more 46 chromosomes- not natural hence we need mechanisms to stop the sperm for a cortical granule reaction. Cleaves the binding sites on the zona pellucida. Changes to chemical properties of the zona pellucida to resist the proteolytic enzymes from the sperm reducing the sperm binding properties of oocyte membrane.
