300816 Lecture 7: Cell biology genes how and they work 1

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Salient points: dna vs rna, transcription, translation, mutations. Dna: stores information, directs the synthesis of proteins, chemically changes (i. e. mutates) genetic characteristics, replicates. Rna: is made in the nucleus and transported to the cytoplasm, the protein coding information in rna comes from dna, rna synthesis follows the base pairing rules, rna is single stranded, three types of rna: Messenger rna-mrna: single stranded, in eukaryotic cells- transported from nucleus to cytoplasm where it is used to direct the making of proteins. Transfer rna- trna: translation, brings amino acids to ribosomes for protein assembly. Ribosomal rna- rrna: structural and functional component of ribosomes along with proteins that also form part of the ribosome. Transcription: produces an rna copy or transcript of a gene from dna, structural gene produced mrna that specifies the amino acid sequence of a polypeptide, a transcription unit is the region from the promoter to the terminator.

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