BIOL 2P97 Lecture 3: p4 - digestive

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Cells that produce hcl: have active and resting state. Would not make sense to continually secrete hcl if you"re not eating continually. The surface layer of cells have little curvatures with loads of proton pumps pumping out acid into environment to gastric gland. When cells are in their resting state. The membrane folds, fold in on themselves and make little vesicles known as tubulovesicles: points all proton pumps interiorly. Once vesicle has a certain amount of protons in vesicle. Once cells are activated, the vesicles fuse with the membrane. Create more folded membranes as in the active form: proton pumps will release protons into the extra cellular fluid. How these cells actually go about producing these acids is: they take a water molecule and the proton pumps can split the water molecule in hydroxide and a proton. The proton is then expelled into the lumen of the stomach. The hydroxide ion will then react with the co2.

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