BIOL 2P98 Lecture Notes - Lecture 17: Vibrio Parahaemolyticus, Cholera Toxin, Vibrio

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Both produce diarrhea, but in ways that are entirely different: v. parahaemolyticus is an invasive organism affecting primarily the colon; v. cholerae is noninvasive, affecting the small intestine through secretion of an enterotoxin. Transmission: vibrio cholerae is often found in the aquatic environment and is part of the normal flora of contaminated water and food. brackish water and estuaries. It is often associated with algal blooms (plankton), which are influenced by the temperature of the water. Human beings are also one of the reservoirs of the pathogenic form of vibrio cholerae: after a disaster, this is a very real danger, since regular, clean water and food supplies are often unavailable. The place cholera calls home: understanding how cholera lives and moves through water has been a goal. Symptoms: v. cholerae produces cholera toxin, the model for enterotoxins, whose action on the mucosal epithelium is responsible for the characteristic diarrhea of the disease cholera.

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