BIOL 1010 Lecture Notes - Lecture 12: Optogenetics, Pharmacogenomics, Allele
21 Dec 2017
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Document Summary
Gene: functional unit of dna that codes for a protein. Genome: the entirety of an organisms genetic material. Genetic association: attempts to distinguish how genotype affects phenotype in populations. Heritability: the extent to which a trait is predictably passed from generation to generation. Linkage disequilibrium (ld): non-random association of alleles that descend from single, ancestral chromosomes. Haplotype: combination of alleles at adjacent locations on a chromosome that are inherited together. Pharmacogenomics: using a patients genomic information to improve the efficacy or educe the side effects of drugs. Pharmacokinetics: how the drug concentration changes as it moves through the body. Pharmacodynamics: how a drug exerts its effects on the body. Allele: one of a number of alternative forms of the same genetic locus. Genotyping: process of determining genetic differences between individuals by using a set of markers.
