NEUR 3200 Lecture Notes - Lecture 15: Membrane Potential, Trpv1, Capsaicin
17 Dec 2017
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Ending of lecture 12 slides (from slide 26) One neuron does all the way from skin to medulla. Corresponds to area that processes that information. Sense small elds = increased sensitivity for ne points. Lateral inhibition = activity of one receptor can change sensitivity of another. New material on pain up to slide 28. Anticipation of pain can result in pain. Pain is subjective, perceptive eg. tough hot stove > pain > withdrawal re ex. Also tells you when there is an injury so you can tend to it. Assumed to indicate pain, although this is not really the case. Doctors ask patients/ questions to rate pain to understand it. Measure physiological processes, they are assumed to be related to event of illness. Congenital insensitivity to pain eg. study of street performers. No feedback of learning that you can"t hurt yourself. This causes engagement in more and more dangerous activities. Caused by one amino acid change in nav1. 7 (sodium channel)
