PSYC 3307 Lecture Notes - Lecture 10: Multiple Sclerosis, Myelin, Arteriole
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Based upon the mri technique"s sensitivity to proton motion (hence transport of molecules) Water in cavities, such as csf, diffuses isotropically (e. g. , equally in all possible directions) H2o diffusion in structured tissues (e. g. , neural tracts) is anisotropic and this physical property can be used to estimate the underlying direction of groups of axons tractography. Contrast agents are typically introduced into the intravascular space by oral or intravenous injection methods. Gadolinium has paramagnetic properties (i. e. , is attracted to an external magnetic field) Can be used to identify areas of blood-brain barrier breakdown. Used for identification of brain tumours, vascular lesions, infections and abscesses and inflammation such as myelin plaques in patients with multiple sclerosis. - used to identify the chemical composition of the material within a given voxel or set of voxels (typically displayed as a histogram). Creatine (cr) a marker of cellular metabolism. Choline (cho) -- an indicator of cellular membrane synthesis.