NURS 2090 Lecture Notes - Etiology, Kernicterus, Immunoglobulin G
16 Apr 2013
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Document Summary
Specific immune response: cell mediated & humoral. ** all cells have a common origin in pluripotent hematopoitic stem cells (originate in bone marrow: lymphoid progenitor cells. B lymphocytes: differentiate into plasma cells and antibody production. Natural killer cells: kill cells they come into contact with. Produce granulocytes and monocytes which phagocytise cells (ben- basophils (allergic rx), eosinophils (parasites) and neutrophils (first responder)), Monocytes differentiate into macrophages, which will display antigen markers to be recognized by b/t cells. Dendritic cells are critical for processing/display of antigens to t cells. (langerhans) Adaptive: is the body"s ability to recognize and then mount a defense against distinct invaders and their products. Humoral immunity: activated b cells, which secrete antibodies against pathogens. Can also have t-independent humoral immunity, which do not rely on th cells, which are rare. T dependent is most common and uses th cells (cd4"s) to activate b cells.
