ANAT 321 Lecture 33: Blood Flow and Ventricles I
4 Dec 2016
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Document Summary
Implications for compulsive behaviour, addiction, reward pathways: the neurons that come from the brainstem and release dopamine travel through the fiber tract. Dopamine neurons in the substantia nigra and the ventral tegmental area project (from the substantia nigra) to the striatum and (from the vta) to the cerebral cortex and subcortical limbic structures (e. g. the amygdala) The neurons are more lateral are located in the sn: goes to the basal ganglia, caudate nucleus of the putamen (striatum) Involved in the basal ganglia loop: degeneration of these neurons that are involved in parkinson"s disease. Reinforcement learning models: dopamine firing encodes a critic signal, which informs other brain regions of the deviation between experience and internally represented goals. The dopamine neurons do not fire when the monkeys receive the juice, but before when they are given the cue: more of a training signal, tells the monkeys what to expect.
