EDKP 495 Lecture Notes - Lecture 5: Baroreceptor, Psych, Insulin
27 Jan 2017
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Detraining/bed rest + effects on what we know about microgravity. Condition in space which only miniscule forces are experienced. *virtual absence of gravity condition of weightlessness. = similar effect of bed rest rapid detraining effect. How are astronauts affected by microgravity: cardiovascular, sleeplessness, bone, muscle, vestibular-related control, loss of vision, depression & anxiety, diminished immune function, microgravity & cardiovascular system. Acute weightlessness induces fluid shift that leads to central volume expansion ~85-192 days on iss. Weightlessness in space = increase in stroke volume & cardiac output + unchanged or slightly. Reduced blood pressure *because fluid accumulate in upper body. Unclear cause of systemic vasodilation leading to reduction. Some vision acuity problems by high in blood pressure = maybe baroreceptor unloading. Results of fluid accumulation in upper body = baroreceptor unloading because no more pressure so increase in stroke volume & cardiac output to maintain blood pressure. *hypothesized to be result of sensitivity to ca2+
