INDS 211 Lecture Notes - Lecture 3: Zona Pellucida, Corpus Luteum, Mons Pubis

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Histology of the female genital tract: introduction. Internal organs: ovaries, oviducts/fallopian tubes, uterus, vagina: external genitalia: mons pubis, labia majora, labia minora, clitoris. Monthly cycle involves ovary and endometrium in a 28-day hormonally controlled cycle of histological changes. Menopause: cyclicity ceases at ~51yo, as a result of depletion of ovarian follicles and reduction in e production [similar to the testes] Ovary functions: (1) gametogenesis (i. e. oogenesis), (2) steroidogenesis (e : pgcs (yolk sac) transform into oogonias undergo massive proliferation between 2nd and 5th month of fetal development (6x105 of. Between 3-7th month fd, most oogonia begin to enter prophase of 1st meiotic division (oocytes) but. Stop at diplotene stage (prior to metaphase: at birth 150,000-400,000 oocytes remain (in both ovaries), but only. 500 will mature (rest degenerate or die by apoptosis: meiosis is arrested until ovulation. Figure: c = cortex (contains follicles); m = medulla (small, highly vascular);

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