PHAR 300 Lecture Notes - Lecture 17: Azoospermia, Nandrolone Decanoate, Gossypol
8 Dec 2017
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Phar 300 lecture 15 contraceptives for men. The male reproductive system: sperm is produced in the testes and goes up into the epididymis via the ducts, and then through the vas deferens ejaculation, male contraceptives are only in the process of being developed. Hormonal control: upper controls are similar to females. The testosterone produced by the leydig cells will act on neighbouring sertoli cells. Fsh will also act on sertoli cells: sertoli cells release paracrine factors, which support germ cell development (differentiation and maturation of sperm). The fact that you can produce sperm is because this loop works. Sertoli cells are inside the seminiferous tubule. All the different stages of development of sperm are embedded within the sertoli cells ( mother cell for germ cell development). Leydig cells are located outside of the seminiferous tubule in the inter-tubular space. These cells are extremely structured and organized.
