BIOCHEM 2EE3 Lecture Notes - Lecture 3: Escherichia Coli, Alpha And Beta Carbon, Zwitterion
Document Summary
Two types of nucleic acids: dna and rna: dna discovered by friedrich miescher group. In rna, the monomer unit has a 5c sugar ribose and 2-deoxyribose in dna. The hydrolysis of this link makes one phosphoric acid and two alcoholic. It cant by itself encode information: nucleic acids are important in info storage an transmission because they are physiological ph heteropolymers. Each monomor has a heterocyclic base or nucleobase always linked to. The 1" carbon of the sugar: two types of heterocyclic bases = purine and pyrimidine. In rna t is replaced by u: transfer rna has many chemically modi ed bases to help stabilize the molecule, most eukaryotic dna has a small prop. of cytosines that are methylated at carbon. The 2" hydroxyl is super important in the rxns. Tautomers = structural isomers differing only in location of h atom and dble. G,t,u can partially isomerize to enol forms.