BIOLOGY 1A03 Lecture Notes - Lecture 19: Petri Dish, Dna Ligase, Ap Endonuclease

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Rosa Da Silva

Document Summary

Viruses have the greatest mutation rate with rna highest probability due to delicate nature of backbone proofreading capability. Hotspots- spots that are prone to mutation. Rate of mutation in males > rate of mutation in. Number of mutations in larger genomes > smaller. Somatic cell mutations (other cells of the body) Mutation in a cell results in mutated daughter cells for a mutated region. The earlier in the developmental cascade a mutation occurs, the larger the spread viruses having the no and females genomes each cell division that can lead to. Mutations are responsible for large array of genes and genetic differences amongst organisms = Mutations in dormant g0 cycle cell are negligible. Cannot be inherited since cell itself not passed on. Cancer cells usually derive from somatic cell mutations but, all mutations much come a single original cell. Germ cells come together to produce new offspring = mutations are passed on = all cells inherit this mutation in offspring.