BIOLOGY 1M03 Lecture Notes - Lecture 27: Rickets, Galactose, Neural Tube Defect

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Mitochodonrial dna sequences from 277 different people around the world. Since it is mitochondrial dna, mutations that have occurred lets us see this in phylogenetic trees. L1, early group: deepest roots, deepest nodes, the most ancient folks, l2 and l3 are also very ancient, gives us info about how people moved out of africa, older lineages from africa have deeper branching. Younger lineages form asia, america, oceana, and europe (shallower branching) Few maps taht refer to the sequences. Mutations, development of l2 and l3: the amount of people in the l1 clade have diminished, n and m, moving out of africa, spreading out to asia. 30 - 50,000 years ago, m and n clades spread into europe and oceania, and then eventually to north america. Neanderthal intergression: homo sapeins came from the cousins of neanderthals, neanderthal dna is connected to homo sapiens dna. If we are not people that are remaining in africa (so not l1, l2 and l3)

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