BIOLOGY 2B03 Lecture Notes - Lecture 4: Electron Microscope, Inner Membrane, Methotrexate
Document Summary
Inside are dense regions that contain protein aggregates: animal cells: responsible for cholesterol synthesis, nerve cells: synthesize plasmalogen for cell membranes, a membrane component that increases the insulating capacity of the membrane. Liver cells: site of oxidation of toxins: plant cells: required for the conversion of fatty acids into carbohydrates, important in seeds, all cells: responsible for the catalysis of fatty acids. Fatty acid metabolism as an energy source: major function = breakdown of very long chain fatty acids through beta oxidation, animal cells: long fa are oxidized to medium chain fa, shuttled to mitochondria for further processing. Catalase is used to identify peroxisomes: when used with fluorescence, we can see the peroxisomes, peroxisomes are not static but are moving around, changing shape, and undergoing both fission and fusion. Synthesized in the cytosol and then transported to the peroxisome: peroxisomal membrane proteins (ex.