BIOLOGY 2B03 Lecture Notes - Lecture 8: Selectin, Glycoprotein, Neural Cell Adhesion Molecule
11 Dec 2015
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Document Summary
Development requires: reiterated mitotic divisions, cell differentiation that defines tissue-specific patterns of gene expression, signaling between cells, cells are able to associated and maintain connections. Embryogenesis: formation of the inner cell mass, forming the embryo: as the number of cells increase, they separate into one of three germ layers. Endoderm, ectoderm, mesoderm: cells must establish and maintain connections. Ability of cells to recognize and adhere to one other demonstrated by h. v wilson. Cells of two species of sponges cells of each organism were separated using a fine mesh and then mixed together. Cells from the same species recognized and associated back together, cells from different species did not associate. Johannes holtfreter used cells form a frog embryo. Took cells from two different germ layers during development and separated individual cells. Two different types of cells mixed together, cells from like tissues recognized one another and associated mimicked the organization seen in the original embryo.
