BIOLOGY 2C03 Lecture 1: Week 1 - Sickle Cell Anemia

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blackherring683

23 Sep 2017

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What is the di erence between phenotype and genotype? phenotype - physical trait/characteristic that is a result of a certain gene genotype - the genetic basis of a trait (i. e aa = heterozygous) Mendel"s rst law two alleles for a trait will segregate from each other during gamete formation and each allele has the same probability of being in that gamete. 1:2:1 genotypic ratio and 3:1 phenotypic ratio crossing hybrid plants gives a 3:1 phenotypic ratio this is because only dominant trait is visible, need 2 recessive alleles to see recessive trait. Complete dominance complete dominance is the result of the same phenotype (trait) occurring whether it is homo or heterozygous genotype (aa or aa) Anemia condition in which there are low numbers of rbc/they are sickle shaped - reducing oxygen intake there are abnormalities in the haemoglobin structure structure of hemoglobin is product of two genes a-globin on chromosome 16.

Related Questions

Question 1

What would be the dimensions of a Punnett square for the cross Hh x hh?

		4 x 4
		2 x 2
		2 x 1
		1 x 1

Question 2

In dogs, the gene for fur color has two alleles. The dominant allele (G) codes for grey and the recessive allele (g) codes for black fur. The female dog is heterozygous. The male dog is homozygous recessive. Figure out the phenotypes and genotypes possible in their puppies by using a Punnett Square. (provide answers on one line with commas between - xx, xx, xx, xx)

Genotypes: , ,

Phenotypes: ,

Question 3

The fundamental Mendelian process which involves the separation of alleles located at the same spot on the chromosome would be called ___.

		segregation
		independent assortment
		continuous variation
		discontinuous variation

Question 4

Using the information given on dominant and recessive traits, state the phenotype for each genotype. Purple flowers are dominant to white flowers in pea plants.

-A.B.C.	PP_____________
-A.B.C.	Pp____________
-A.B.C.	pp_______________

A.	purple flowers
B.	purple flowers
C.	white flowers

Question 5

In dogs, the gene for fur color has two alleles. The dominant allele (G) codes for grey and the recessive allele (g) codes for black fur. The female dog has black fur and the male dog is homozygous dominant. Make a Punnett square to determine the chance of getting each genotype and phenotype below.

-A.B.	Probability of GG:
-A.B.	Probability of Gg:
-A.B.	Probability of gg:
-A.B.	Probability of gray fur:
-A.B.	Probability of black fur:

A.	100
B.	0

Question 6

Using the information given on dominant and recessive traits, state the phenotype for each genotype. Round seeds are dominant to wrinkled seeds in pea plants.

-A.B.C.	RR______________
-A.B.C.	Rr _____________
-A.B.C.	rr ____________

A.	round seeds
B.	wrinkled seeds
C.	round seeds

Question 7

Using the information given on dominant and recessive traits, state the phenotype for each genotype. Hairy knuckles are dominant to non-hairy knuckles in humans.

-A.B.C.	HH_____________
-A.B.C.	Hh ___________
-A.B.C.	hh _________________

A.	non-hairy knuckles
B.	hairy knuckles
C.	hairy knuckles

Question 8

An allele is ___.

		one of the bases in DNA
		an alternate form of a gene
		another term for epistasis
		present only in males and is responsible for sex determination

Question 9

In a cross of a round hybrid pea with a true breeding round parent (Rr x RR), what genotypic proportions would be observed in the offspring?

		Half heterozygous, half homozygous dominant
		Half round, half wrinkled
		All heterozygous
		All round

Question 10

What would be the dimensions of a Punnett Square depicting a dihybrid cross?

		1 x 4
		2 x 4
		4 x 4
		2 x 2

QUESTION 1

Jim is blood type A, his brother John is type O and his sister Jane is type AB. What are the genotypes of their parents?

Which of the following is true for alleles that show incomplete dominance?

Heterozygotes have a genotype like the dominant allele.

Homozygotes have a genotype like the recessive allele.

Heterozygotes have a phenotype intermediate between the dominant and recessive alleles.

Homozygotes have the same phenotype as the heterozygotes.

QUESTION 3

Which principle of inheritance concluded that when games are formed in meiosis, the two alleles of each gene separate from one another, and each gamete receives only one allele?

independent assortment

Which term best describes a condition in which alleles at one locus can alter the expression of alleles at another locus?

polygenic inheritance

A single unit of genetic information located on a chromosome defines:

The physical expression (appearance or function) of an organism's genes defines:

genotype

a single characteristic

Palomino horses (golden color with a blond mane) are an incompletely dominant trait produced by the combination of the chestnut color allele and the cream color allele. If you wanted to produce as many palominos as possible, which mating strategy below would be the best choice?

Which term best describes the effect of a single gene on multiple aspects of the phenotype?

polygenic inheritance

QUESTION 9

Which term best describes the separate expression of both alleles for a single trait in the same cell?

polygenic inheritance

QUESTION 10

One form of a gene found on a single chromosome defines:

A chocolate lab (whose mother was a yellow lab) is mated with a black lab whose genotype is BbEe. What fraction of the offspring would be expected to be yellow labs?

What type of allele is always expressed regardless of whether the individual is homozygous or heterozygous for it?

Both the dominant and recessive alleles

Given the parents AABBGgHhrr Ã AabbGgHhRr, assume simple dominance and independent assortment. What proportion of the progeny will be expected to have the genotype AaBbggHHrr?

___________________ is defined as having two of the same type of allele for a particular trait.

The physical position of an allele on a single chromosome defines:

Which term best describes two or more genes affecting the phenotype in an additive fashion?

codominance

polygenic inheritance

1. A person is described as a carrier for a particular genetic disease. What does this tell you about their genotype?

2. For any given gene, the principle of independent segregation predicts that each gamete produced as a result of meiosis will contain ____________________

3. A pair of alleles is said to be heterozygous when:

4. In a diploid species, cells can have up to ___ alleles of a particular gene.

5. In a cross between a homozygous dominant parent and a homozygous recessive parent, the number of phenotypic classes observed in the offspring is ______

6. For a person of genotype Xx, the genotype of their gametes may be ______________

7. In a "test cross", an individual of unknown genotype is crossed with a ___ individual to determine the unknown genotype.

8. An albino woman has a child with a phenotypically normal man with no family history of albinism (which is a rare recessive disorder). What percentage of their children are likely to be albino?

9. An individual with the dominant phenotype, but an unknown genotype, is test-crossed, and all of the offspring exhibit the dominant phenotype. The genotype of the unknown individual is ______________

10. If two heterozygous individuals for a recessive disease (carriers) have a child, what is the chance that their child will develop the disease?

11. In a monohybrid cross between two true-breeding parents that both exhibit the dominant phenotype, ___ percent of the offspring will exhibit the recessive phenotype.

12. In a particular type of tomato plant, red fruit is dominant over yellow fruit, and dwarf height is a recessive trait. If two heterozygous plants were crossed, what proportion of the offspring would show the dominant phenotype?

13. In a cross between a BbRr individual and a BBRR one, what do the following represent: BR, Br, bR, br?

14. In humans, the gene that determines whether an embryo develops as a male or a female is carried on _____________

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BIOLOGY 2C03 Lecture 1: Week 1 - Sickle Cell Anemia

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