BIOLOGY 2EE3 Lecture Notes - Lecture 14: Pentose Phosphate Pathway, Electron Acceptor, Oxidative Phosphorylation

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Energy: products of a chemical reaction must have a lower free energy than the reactants, energy released is known as gibbs free energy (g) Catabolism: breaking down larger molecules to obtain energy and smaller precursors. Anabolism: use of smaller precursor molecules and energy from catabolism to build macromolecular cell components. Simplified scheme of major components of carbon and energy metabolism. Glycolysis: different glycolytic pathways (lysis of glucose) can be used by different organisms, embden-meyerhof-parnas (emp, entner-doudoroff, pentose phosphate, each is capable of generating energy and/or precursor molecules for use in other metabolic pathways. Entner-doudoroff pathway: alternate route to pyruvate, produce less atp than emp pathway, metabolizes sugars via c6-intermediate known as kdpg, found in several aerobic and anaerobic bacterial species. Pentose phosphate pathway: technically not glycolysis, does not produce pyruvate, produces precursors for other pathways, produces nadph + h+ for later use, found in most microorganisms. Clostridium acetobutylicum ferments starch to make acetone (3 parts), n-

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