HTHSCI 1H06 Lecture Notes - Lecture 8: Positive Feedback, Lysozyme, Defensin
27 Jul 2018
School
Department
Course
Professor
Document Summary
Recruited or induced innate immunity (aka inflammation) Immunitas (latin): protection from a duty to the state. Immune system is primarily concerned with the maintenance of homeostasis. Marcus annaeus used immunity in a medical term: when people survived their first snake. Edward jenner and smallpox smallpox happens they didn"t die from it and they were also subsequently immune to smallpox. Realized that milkmaids didn"t get the same form of smallpox, instead they got cowpox and. Cowpox was a stimulus so the immune system can make something to knock it down when. Smallpox became officially eradicated by giving people a little bit of the cowpox virus. Vaccination is introducing all or subunits of an attenuated or inactivated pathogen. Intrinsic barrier: first defence, keeps pathogen out without infection (cid:3203) if breached, innate immune system has resident defences to remove infectious agent. Induced innate response: third response: recruits cells circulating in bloodstream to get them. Adaptive is the last response to destroy everything.
