HTHSCI 1LL3 Lecture Notes - Lecture 4: Alpha And Beta Carbon, Amine, Isoleucine

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 1LL3
• Professor: Dr.Mc Curdy

Document Summary

All the proteins in the body are made from the 20 amino acids coded for by our dna. The u(cid:374)i(cid:395)ue se(cid:395)ue(cid:374)(cid:272)e of a(cid:373)i(cid:374)o a(cid:272)ids i(cid:374) ea(cid:272)h p(cid:396)otei(cid:374) (cid:894)the p(cid:396)i(cid:373)a(cid:396)(cid:455) se(cid:395)ue(cid:374)(cid:272)e(cid:895) p(cid:396)edi(cid:272)ts its" conformation. The properties of side chains on each amino acids dictates the associations between them, leading to the conformation of the protein. A, g, c, t specify one amino acid. Amino acids are all the same but the side chains are different. All of the 20 amino acids have a common structure. The alpha carbon is substituted with an amino group, a carboxylic acid group, a hydrogen and an individual side chain. The (cid:272)he(cid:373)i(cid:272)al p(cid:396)ope(cid:396)ties of the side (cid:272)hai(cid:374) of its" a(cid:373)i(cid:374)o a(cid:272)ids dete(cid:396)(cid:373)i(cid:374)e ho(cid:449) a p(cid:396)otei(cid:374) can interact with other molecules. At ph(cid:455)siologi(cid:272)al ph a(cid:373)i(cid:374)o a(cid:272)ids e(cid:454)ist as (cid:862)z(cid:449)itte(cid:396)io(cid:374)s(cid:863), (cid:449)he(cid:396)e (cid:271)oth the a(cid:373)i(cid:374)o a(cid:374)d carboxylic acid groups are charged. At this ph, the molecule is neutral, this is not the case when the ph changes.