HTHSCI 1LL3 Lecture Notes - Lecture 6: Eukaryotic Dna Replication, Semiconservative Replication, Topoisomerase
6 Mar 2017
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G2 the cell assesses whether or not the dna has been replicated completely or correctly. If not, the cell should not go through to mitosis: m where the cells divide. Topoisomerase: an enzyme that can break and rejoin the strands to relieve the tension from twisting. Telomeres: the ends of linear chromosomes have many nucleotide repeats ttaggg in humans, these exist so that when chromosomes are replicated, and the lagging strand is shorter, replication does not result in shortening of the coding regions. It is a complex of proteins, rna and an enzyme that lengthens the ends of the chromosomes. Reverse transcriptase: telomerase contains a reverse transcriptase, similar to the polymerase used by rna- containing viruses such as hiv, a single strand of rna is reverse transcribed to single-stranded dna, complementary. Dna: the rna is removed and dna is double stranded.
