HTHSCI 1LL3 Lecture Notes - Lecture 2: Metabolic Acidosis, Respiratory Acidosis, Blood Gas Tension
6 Mar 2017
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Document Summary
Function in acid-base balance: the regulation of the partial pressure of co2, normal value 35-45mmhg, related to the depth and rate of air movement in the lungs. Pao2: arterial partial pressure of oxygen. Role in acid-base balance: maintain the concentration of bicarbonate in the blood at 24 m eq/l. They maintain acid-base balance through 3 mechanisms: reabsorption of filtered bicarbonate, titratable acid formation, excretion of nh4. Identify the ability of the lungs to oxygenate blood. Venous blood gases: determine tissue oxygenation. Hemoglobin saturation remains above 90% if: pao2 > 60mhg. If pao2 < 60mmhg it may indicate a reduction in hgb saturation and impaired oxygen delivery to tissues. The ability of the lungs to excrete co2. May be elevated in respiratory acidosis or in a compensated metabolic alkalosis: bicarbonate level. Level from abg or the serum bicarbonate from the blood measured. Can be used to assess acid-base status: the base excess/deficit.
