HTHSCI 1LL3 Lecture Notes - Lecture 7: Thiamine Pyrophosphate, Hexokinase, Carbonic Anhydrase
23 Apr 2018
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Document Summary
Catalytic action of enzymes: enzymes increase the rate of chemical reactions, each enzyme is specific to one reaction, bind substances that are reacting (substrates) and release the products one the reaction is complete. Steps in an enzyme-catalyzed reaction: bind to a substrate, conversion of substrate to product, release of product. Speeds up the reaction may proceed: the active side of the molecule is dependent on the amino acids that are located there. Enzyme cofactors: enzymes often require a cofactor to bind to it in order for it to function, essential to the enzymes function, cofactors help lower the energy required to cause the reaction to start. Substrate fits into the enzyme like a key. If it fits, then the reaction will proceed, and be catalyzed. Some enzymes work best in acidic environments, such as the stomach, while others work better above the ph of the stomach.
