HTHSCI 2H03 Lecture Notes - Lecture 8: Atrophic Vaginitis, Abdominal Pain, Cervical Dilation

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Water soluble endocrine hormones: typically, binding of water soluble hormones to cell surface receptors leads to the manufacture of second messengers (e. g. camp or ip3) which alter cell function. Water soluble endocrine hormones that activate g proteins include: norepinephrine, epinephrine, oxytocin, some water-soluble hormones bind to extracellular receptors that activate protein kinases directly (no 2nd messengers) Dna: these hormones form a complex with their receptor and then bind to dna, act as a transcription factor. Gonadotropin releasing hormone (gnrh) (hypothalamus) -> luteinizing hormone (lh) and. Follicle stimulating hormone (fsh) (anterior pituitary) -> sex steroids (progesterone, estrogens and androgens), produced in the gonads -> increased sex drive (libido- testosterone), secondary sexual characteristics (body hair, muscle growth et(cid:272) much depends on gender) Increased sex drive and secondary characterizes -> signals hypothalamus to stop releasing. Gnrh -> anterior pituitary stops receiving gnrh -> anterior pituitary stops releasing lh and.

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