HTHSCI 2H03 Lecture Notes - Lecture 2: Human Body Weight, Hyperlipidemia, Arteriole
29 Apr 2016
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Document Summary
Obesity associated with 3-5 times increased risk. Diabetes associated with 2-3 times increased risk. Disproportionately affects those of aboriginal, african or south asian descent. No known cause represents 90-95% of cases. Genetic predisposition, dietary salt intake, adrenergic tone. Known cause represents 5-10% of cases. Prolonged force on vessels thickens muscles in arterial system - loss of responsiveness. Heart constantly works harder to expel blood against a greater force, increasing the workload of the heart left ventricle thickens. Increased force damages inner lining of arteries - susceptible to atherosclerosis and to narrowing of the vessel lumen. Tiny vessels are damaged and destroyed leading to losses in vision, kidney function and cerebral function. Cerebrovascular disease, coronary artery disease, congestive heart failure, cardiac death, renal failure, peripheral vascular disease, dementia. High in fresh vegetables and fruit, low fat dairy products low in saturated fats and. Minimum 4 days/week for 30-60 minutes, moderate cardio. Maintenance of ideal body weight cholesterol, high in dietary bre.
