HTHSCI 3I03 Lecture Notes - Lecture 1: Respiratory Tract, Septic Shock, Aureus

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Staphylococcus aureus: gram +"ve, greek origin for bunch of grapes, aureus refers to gold colour on blood agar plates due to b-hemolytic activity. Infections range from asymptomatic colonization, to local skin infections/abscesses, to septic shock. Staphylococcus aureus: can be spread from person to person by direct contact or by sharing person items (towels, razors, efficient colonizer of humans (15-30% of people are persistently colonized in the upper respiratory tract) Extracellular bacterial infection by s. aureus: hallmark of most minor staphylococcal infections are abscesses filled with pus (boils/furuncle, carbuncles) Able to cause a wide range of infections on a wide range of tissues: skin boils, lungs pneumonia, heart endocarditis, urogenital tract utis, systemic toxic shock syndrome.

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