LIFESCI 4W03 Lecture Notes - Lecture 10: Caffeine, Inverse Relation, Diazepam

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Inverse relationship between coffee consumption and: decreases risk of suicide. Colorectal cancer and liver disease: increases cognitive function concentration and problem solving, decreased mortality in smokers. Caffeine consumption throughout pregnancy is associated with an increased risk of fetal growth restriction. Positive association between coffee consumption and all-cause and cvd mortality in men and women younger than 55. Findings suggest that younger people should avoid heavy consumption (>4 cups/day) Increased risk for hypertension for greater than 5 cups/day. Benefits: rct w/ 103 patients (4 cups), acute ingestion. Benefits seen as less when consuming unfiltered vs filtered coffee. See health benefits with coffee but not in regards to caffeine intake. Saw decrease risk of myocardial infarction with moderate risk of coffee intake vs non-coffee drinkers (<300mg/day vs 0mg/day) Small increase in blood pressure occasional coffee drinkers. Increase in homocysteine plasma levels with 4. 5 cups per day. Increase in total cholesterol, increase lcl-c and increase triglycerides with 6 cups or more per day.

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