NURSING 1I02 Lecture Notes - Lecture 7: Peripheral Artery Disease, Engineering Controls, Immunosuppression

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Health care associated infections are the most common serious complication of hospitalization (one in nine get infection as a consequence of their hospital stay) In canada, estimate that 220,000 incidents of ha occur each each year, resulting in more than 80000 deaths. Health care associated infection were the 11th leading cause of death two decades ago, but are now the fourth leading cause of death. *risk of getting sick: tired, stress, less exercise, poor diet. Age: infants and older adults at increased risk. Stress: hormones released decrease inflammatory responses; prolonged stress decrease resistance to infection. Chronic disease: immune system, burns, peripheral vascular disease, emphysema and bronchitis. Medical therapies/immunosuppression: chemotherapy, organ transplants, steroid (anti- inflammatory) therapy. Immune response protects the body by neutralizing pathogen and repairing damaged body cells. Non-specific protection: normal flora, body systems defences (skin, saliva, respiratory cilia, gastric acid) Inflammation: vascular reaction delivers fluid, blood products, nutrients to area of tissue injury.

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