NURSING 2LA2 Lecture Notes - Lecture 7: Airway Obstruction, Squamous Metaplasia, Alpha-1 Antitrypsin
8 Mar 2017
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Document Summary
Copd: major respiratory disease in canada, often preventable, under diagnosed, prevalence of copd is underestimated b/c those w/ early symptoms of copd are not recognized and/or don"t seek tx, affects at least 700 000 adults which is approx. Copd phenotypes: copd is not a single disorder, these different phenotypes may overlap and include chronic bronchitis, emphysema, and. It is a group of disorders that are characterized by airflow limitation bronchiectasis: chronic bronchitis: characterized by airway inflammation and obstruction of the major and small airways. Episodic wheeze with chest tightness, cough and dyspnea. Hx allergies and sinusitis rare, hx resp infections. Fragile epithelium, thickening of basement membrane, mucus gland metaplasia and enlargement. Squamous metaplasia of epithelium, parenchymal destruction, mucus gland metaplasia and enlargement. Copd: respiratory disorder largely caused by smoking, characterized by progressive, partially reversible airway obstruction and lung hyperinflation, systemic manifestations and increasing frequency and severity of exacerbations.
