NURSING 2LA2 Lecture 5: Pathophysiology for Nursing- copd
20 Jan 2019
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Pathophysiology for nursing copd: copd underdiagnosed, affects at least 700 000 adults, app 4. 4% canadians aged 35 years or older (2013) #1 cause of copd, 15-20% smokers copd dx; 80-90% dx copd have hx of smoking. Long-term inhalational exposure to: occupational dusts/chemicals; indoor pollution from heating and cooking with biomass fuels; outdoor pollution: other risk factors. Severe childhood respiratory infections, asthma, airway hyperresponsiveness, nutritional compromise, impairment of fetal development resulting in low birth weight, infants who develop bronchopulmonary dysplasia: most important factor is smoking. Copd phenotypes: not a single disorder and group of. Disorder that are characterized by airflow limitation and phenotypes may overlap and include the following. Airflow limitation mechanisms: loss of lung elastic recoil, occurs with emphysema due to protease mediated degradation of connective tissue elements in lungs, peribronchiolar fibrosis. Increased airway secretions: copd there is mucus hyperplasia and increased expression of mucin genes. Inflammation and oxidant injury play a role in mucus hypersecretion: airway smooth muscle.
