NURSING 2LA2 Lecture Notes - Lecture 3: Vascular Permeability, Necrosis, Neutrophil

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Causes of inflammation: microbes immune reactions between antigen and antibody trauma, burns, physical or chemical agents, oxygen deprivation, nutrient deprivation, genetic or immune defects tissue necrosis temperature extremes ionizing radiation. Immune systems: we develop immunity based on our individual experiences with exposure to pathogens and foreign antigens over our lifetime, humoral response response comes from the blood or plasma. In immunity involves the formation and action of antibodies: cellular response a cell-derived process. In immunity involves lymphocytes: defence mechanisms, natural barriers the epithelial layer of skin and mucous membranes lining the gi, Basophils: produce lipid mediators and cytokines to induce the inflammatory response, bind to ige to release histamine and vasoactive agent important in the allergic reaction and hypersensitivity diseases interact with the immune system. Mediators of inflammation: mast cell degeneration, activation of plasma protein systems, release of cell derived mediators.

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