BIOL 200 Lecture Notes - Lecture 12: Nuclear Pore, Glycosylation, Cytosol
Document Summary
Internal cell structures: endoplasmic reticulum and golgi complex. Rough er function: produce lysosomal enzymes, glycosidases, proteases, other related enzymes, manufacture proteins for export from cell, manufacture integral membrane proteins ex. Ser in specialty cells: different functions in each cell type (ex 1) adrenal gland cells: manufacture glucocorticoid hormones like cortisol, research example: Cholesterol and steroid synthesizing smooth endoplasmic reticulum of adrenocortical. Cells contains high levels of proteins associated with the translocation channel. Virginia h. black archana sanjay klaus van leyen brett lauring gert kreibich. Sr membrane has lots of sarco/endoplasmic reticulum atpase (serca) Lumen contains lots of calsequestrin (ca2+ binding protein) Opens when triggered by calcium entering cell from nerve impulse (also triggered by caffeine) Released calcium is signal for muscle contraction. Intake from smooth(ish) er: anterograde movement, vesicles from ser to cis-face of golgi, copii proteins coat vesicles (target them for golgi, retrograde movement also observed. Some vesicles move from golgi to er.