BCHM 102 Lecture Notes - Lecture 23: Citric Acid Cycle, Lipoprotein, Medical Emergency
2 Dec 2016
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Lecture twenty-three - hypoglycemia & feed fast cycle. Lecture objectives: describe hypoglycemia, its symptoms and the bodies coping mechanisms, discuss the mechanisms controlling flow of intermediates through metabolic pathways in absorptive state, understand the tissue specific changes in metabolism in the absorptive state. Body has a number of redundant systems that prevent and correct hypoglycemia. Symptoms of hypoglycemia: divided into 2 classes, adrenergic, results from elevated epinephrine. Fear, tremors and sweating: neuroglycopenic, results from decreased brain glucose. Impaired brain function, confusion, seizures, coma or death (if left untreated) the brain can use ketone bodies but it is not enough. Insulin-induced most common: occurs in diabetics being treated with insulin (fine line too much insulin, mild cases are treated with oral glucose administration. Severe cases (unconscious) typically given glucagon subcutaneously or intramuscularly: postprandial (reactive) hypoglycemia - second most common, caused by exaggerated insulin release following a meal.
