MICR 121 Lecture Notes - Lecture 10: Hepatitis C Virus, Viral Hepatitis, Viremia
11 Apr 2018
School
Department
Course
Professor
Document Summary
Hepatitis and hepatitis virus general term referring to inflammation of the liver causes: infectious: viral, bacterial, fungal, parasitic: non-infection: alcohol, drugs, autoimmune, metabolic diseases. 5 viruses: a, b, c are the most common, d, e viruses enter the body via different means but has a predilection for hepatocytes, so they hone in one the liver and infect hepatocytes. Pread (cid:271)y eati(cid:374)g other people"s poop or things grown in poop (faecal: oral route of transmission: viral infection: of liver spreads when faecal matter enters the mouth. May last several weeks and can be debilitating but most people recover completely. Symptoms: nausea, vomiting; usually asymptomatic disease especially in kids. Initially debilitating; high burden, high transmission; via food (not washing hands) Single most important determinant of illness severity is age: adults: 75% symptomatic, often w jaundice, <2 years of age: 90% asymptomatic, 5-14: acute hav infection. Clinical illness includes: fever, malaise, appetite loss, nausea, abdominal pain, jaundice.
